Arsenic Trioxide is formulated as a sterile, nonpyrogenic, clear solution of arsenic trioxide in water for injection using sodium hydroxide and dilute hydrochloric acid to adjust to pH 8. Arsenic Trioxide Injection is preservative-free. Arsenic trioxide, the active ingredient, is present at a concentration of 1.0 mg/mL.

There are many options to help minimize or prevent side effects. There is no relationship between the presence or severity of side effects and the effectiveness of the medication. Concomitant Strong CYP3A4 Inhibitors: The concomitant use of strong CYP3A4 inhibitors should be avoided (e.g. ketoconazole, itraconazole, clarithromycin, atazanavir, indinavir, nefazodone, nelfinavir, ritonavir, saquinavir, telithromycin, and voriconazole).Grapefruit juice may also increase plasma concentrations of sirolimus (a major metabolite of temsirolimus) and should be avoided.

Arsenic trioxide package insert

Cardiac Conduction Abnormalities: Arsenic trioxide can cause QTc interval prolongation, complete atrioventricular block, and a torsade de pointes-type ventricular arrhythmia, which can be fatal. Arsenic Trioxide Injection. Print this page Send link to a friend. P.I. Unit Of Sale NDC 63323-Unit Of Use NDC Product Number P.I. = Package Insert : SDS: Enlarge ARSENICUM OXYDATUM- arsenic trioxide pellet Hahnemann Laboratories, Inc. Disclaimer: This homeopathic product has not been evaluated by the Food and Drug Administration for safety or efficacy. FDA is not aware of scientific evidence to support homeopathy as effective. ARSENICUM ALBUM- arsenic trioxide globule True Botanica, LLC. Disclaimer: This homeopathic product has not been evaluated by the Food and Drug Administration for safety or efficacy.

P.I. Unit Of Sale NDC 63323-Unit Of Use NDC Product Number P.I. = Package Insert : SDS: Enlarge ARSENICUM OXYDATUM- arsenic trioxide pellet Hahnemann Laboratories, Inc. Disclaimer: This homeopathic product has not been evaluated by the Food and Drug Administration for safety or efficacy.

2019-08-29

However, a pilot study of treatment with oral arsenic realgar-Indigo naturalis formula (RIF) plus ATRA without chemotherapy, which has a more A package insert typically includes information regarding specific indications, administration schedules, dosing, side effects, contraindications, results from some clinical trials, chemical structure, pharmacokinetics and metabolism of the specific drug.By carefully reviewing the package insert, you will get the most complete and current information about how to safely use this drug. Arsenic trioxide serious interactions with 73 different drugs. Arsenic trioxide has moderate interactions with 34 different drugs. Arsenic trioxide has no listed mild interactions with other drugs.

arsenic trioxide therapy (n = 8) were further treated with IV arsenic trioxide (10mg/day) and oral ATRA (45mg/m2/day) until CR3, followed by consolidation with arsenic trioxide + ATRA, given every 14 days for 4-6 weeks for 6 cycles. Of the 3 regimens, chemotherapy was associated with a CR2 rate of 47% and

Each vial contains 200 mg of dacarbazine (the active ingredient), citric acid monohydrate and mannitol. Arsenic trioxide is readily absorbed by the digestive system: toxic effects are also well known upon inhalation or upon skin contact.

• Before intiating therapy, perform a 12-lead ECG, assess serum electrolytes and creatinine, correct preexisting electrolyte HIGHLIGHTS OF PRESCRIBING INFORMATION TRISENOX® (arsenic trioxide) injection These highlights do not include all the information needed to use TRISENOX safely and effectively. See full prescribing information for TRISENOX. TRISENOX® (arsenic trioxide) injection, for intravenous use Initial U.S. Approval: 2000 WARNING: DIFFERENTIATION SYNDROME, 8 TRISENOX™ is available in 10 mL, single-use ampules containing 10 mg of arsenic trioxide. 9 TRISENOX™ is formulated as a sterile, nonpyrogenic, clear solution of arsenic trixoide in 10 With TRISENOX ® (arsenic trioxide) injection + tretinoin 1. Indication.
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Arsenic trioxide should be diluted with 100 to 250 mL 5% Dextrose Injection, USP or 0.9% Sodium Chloride Injection, USP, using proper aseptic technique, immediately after withdrawal from the ampule.

Arsenic trioxide has been established for use in both relapsed and front-line treatment of acute promyelocytic Arsenic trioxide (trisenox) [package insert]. Arsenic trioxide is FDA approved for the treatment of acute promyelocytic leukemia A package insert is required by the FDA and contains a summary of the Aug 18, 2015 The educational content on WikiDoc drug pages is based upon the FDA package insert, National Experienced Physician and Institution: Arsenic trioxide injection There is a Black Box Warning for this drug as shown he Arsenic Trioxide Injection. Print this page · Send Product Number, Description, Strength (Concentration), Fill Volume (Container P.I. = Package Insert, SDS Jun 10, 2020 ATO, arsenic trioxide; ATRA, all-trans-retinoic acid.
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A package insert typically includes information regarding specific indications, administration schedules, dosing, side effects, contraindications, results from some clinical trials, chemical structure, pharmacokinetics and metabolism of the specific drug.By carefully reviewing the package insert, you will get the most complete and current information about how to safely use this drug.

Discuss with your healthcare team. Arsenic trioxide 1327-53-3 1 mg/ml by weight 215-481-4 Product: Arsenic Trioxide 1 mg/mL Solution for Infusion | Manufacturer: NerPharMa srl | Revison:01/11/2018, Version:0 Page 1 of 5 2015-05-12 The active substance in Trisenox, arsenic trioxide, is a chemical that has been used in medicines for many years, including for the treatment of leukaemia.